Genetic examinations list

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MTM1 gene testing – X-linked myotubular myopathy congenital

Sequencing of 14 coding exons in the MTM1 gene.

Material:

Peripheral blood, Buccal swab …
Peripheral blood, Buccal swab, Isolated DNA from blood, Isolated DNA from chorionic villi, Isolated DNA from amniotic fluid, Isolated DNA from cordocentesis, DNA isolated from the product of conception, Cultured cells

Turnover Time:

3 weeks

STATIM

1 week

EXOSC3 gene testing – pontocerebellar hypoplasia type 1 (PCH1)

Sequencing of 1 coding exon in the EXOSC3 gene for PCH1 (pontocerebellar hypoplasia type 1).

Material:

Peripheral blood, Buccal swab …
Peripheral blood, Buccal swab, Isolated DNA from blood, Isolated DNA from chorionic villi, Isolated DNA from amniotic fluid, Isolated DNA from cordocentesis, DNA isolated from the product of conception

Turnover Time:

3 weeks

STATIM

1 week

MARVELD2 gene testing (exon 4) – early non-syndromic AR deafness

Sequencing the coding region of exon 4 in the MARVELD2 gene, which is a common cause of hearing loss in the Roma ethnic group.

Material:

Peripheral blood, Buccal swab …
Peripheral blood, Buccal swab, Isolated DNA from blood, Isolated DNA from chorionic villi, Isolated DNA from amniotic fluid, Isolated DNA from cordocentesis, DNA isolated from the product of conception, DNA isolated from cultured cells

Turnover Time:

3 weeks

STATIM

1 week

Familial hypercholesterolaemia – FH test

Testing for familial hypercholesterolaemia (FH) using SNP array.

Material:

Peripheral blood, Isolated DNA from blood

Turnover Time:

4 weeks

STATIM

3 weeks

Fragile X syndrome – detection of CGG repeat expansion in the FMR1 gene

The testing is performed to determine the presence and extent of CGG triplet expansion in the IT15 region of the FMR1 gene.

Material:

Peripheral blood, Buccal swab …
Peripheral blood, Buccal swab, Isolated DNA from blood, Chorionic villi, Amniotic fluid, Cord blood, Conception product, Cultured cells, Isolated DNA from cordocentesis, Isolated DNA from chorionic villi, DNA isolated from the product of conception, Isolated DNA from amniotic fluid

Turnover Time:

3 weeks

STATIM

3 days