Genetic examinations list

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Karyotyping of the couple, preconception diagnosis

Karyotyping to determine numerical and structural chromosomal aberrations (deviations) in patients planning a family.

Material:

Peripheral blood

Turnover Time:

8 weeks

STATIM

4 weeks

Karyotyping of the patient, preconception diagnosis

Karyotyping to determine numerical and structural chromosomal aberrations (deviations) in patients planning a family.

Material:

Peripheral blood

Turnover Time:

8 weeks

STATIM

4 weeks

Response to hormonal stimulation – Ser680Asn polymorphism in the FSHR gene

Testing for p.Ser680Asn polymorphism in the FSH receptor gene (FSHR) by real-time PCR. This is aimed at investigating the Ser680Asn to Ser680Ser change that is associated with low sensitivity of FSHr to gonadotropins.

Material:

Peripheral blood, Isolated DNA from blood

Turnover Time:

3 weeks

STATIM

1 week

Karyotyping from AMC

Foetal karyotyping from amniotic fluid to determine chromosomal aberrations of the foetus.

Material:

Cultured cells

Turnover Time:

2 weeks

Karyotyping from cordocentesis

Foetal karyotyping from cord blood to determine chromosomal aberrations of the foetus.

Material:

Cultured cells

Turnover Time:

2 weeks

RNA analysis of selected mutations

Complementary RNA analysis to the result obtained from testing for congenital predisposition to certain tumour types by CZECANCA cancer panel.

Material:

Peripheral blood RNA

Turnover Time:

3 months